Research Article

Impact of Pharmacy-Led Medication Review on Chronic Disease Outcomes in Kigali

A pragmatic evaluation of pharmacist-led medication reviews integrated into primary care services in Kigali, Rwanda.

Open accessIRU Article ID: IRU-J-2025-0007DOI: 10.1234/iru.j.2025.0007
Received: 15 January 2025Accepted: 10 March 2025Published: 25 March 2025

Authors & Affiliations

Dr. Aline UwizeyeEmmanuel N.Dr. Theoneste
1 Department of Pharmacy, Kigali University Teaching Hospital, Rwanda.
2 Community Pharmacy Practice Network, Kigali, Rwanda.
Corresponding author: aline.uwizeye@example.org

Abstract

Background: Chronic disease management in low-resource settings often suffers from fragmented medication information and limited follow-up. Pharmacist-led medication review models may improve safety and outcomes but evidence from African settings remains limited.
Methods: We conducted a pragmatic, prospective study integrating structured medication reviews into routine visits for adults with hypertension and/or diabetes in primary care clinics in Kigali.
Results: Over six months, pharmacist-led reviews identified and resolved a range of drug therapy problems, and were associated with improvements in clinical markers and self-reported adherence.
Conclusion: Pharmacy-led medication review services are feasible in Kigali and show promise for supporting chronic disease outcomes, with lessons that can be applied across similar contexts.
Keywords:
pharmacy practicemedication reviewchronic diseasehypertensiondiabetesRwanda

Introduction

Chronic diseases such as hypertension and diabetes are increasing in prevalence in Rwanda and across the region. Medication review is a structured, pharmacist-led process designed to optimise medicines use and improve outcomes. However, evidence on its implementation in routine African primary care is limited. This article describes the implementation and early outcomes of a pharmacy-led medication review service integrated into primary care clinics in Kigali, with a focus on feasibility and impact on patient outcomes.

Methods

Study design and setting

We conducted a pragmatic, prospective service evaluation in selected primary care clinics in Kigali between January and June 2024. Clinics were selected to represent a mix of public and private facilities. Adult patients (≥18 years) with a diagnosis of hypertension, diabetes, or both who were attending follow-up appointments and taking at least one chronic medication were eligible for inclusion.

Figure 1. Sample flow diagram placeholder
In a real implementation, this area would display the study flow diagram or other figure associated with the methods.

Results

A total of 210 patients received at least one pharmacist-led medication review during the evaluation period. The median number of medications per patient was 4 (IQR 3–6). Across all reviews, common drug therapy problems included suboptimal dosing, potential interactions, and gaps in adherence support.

Table 1. Summary of baseline characteristics (placeholder)
Replace this placeholder with an HTML table or embedded image representing the actual results, depending on your preferred workflow.

Discussion

Our evaluation suggests that pharmacist-led medication reviews can be integrated into primary care workflows and may contribute to improved chronic disease management. Future work should evaluate cost-effectiveness, long-term outcomes, and strategies for scaling and sustaining such services within broader health system reforms.

Conclusion

Pharmacy-led medication review services in Kigali demonstrate feasibility and early impact on chronic disease outcomes. IRU Journal welcomes further studies that explore implementation, outcomes, and adaptations of pharmaceutical care models in diverse settings.

References

  1. Example, A., & Colleague, B. (2023). Title of a relevant article. Journal Name, 10(2), 100–110.
  2. Another, C. D. (2022). Another reference example. Another Journal, 5(1), 1–9.

Related Articles